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. 2011 Dec;164(7):1829–1844. doi: 10.1111/j.1476-5381.2011.01475.x

Figure 7.

Figure 7

Recovery of T-cells via increased proliferation of precursor cells. Mice were treated with morphine or placebo for 7, 14 or 21 days. Untreated control mice are shown as a dashed line. Thymocytes were analysed as described in Figures 4 and 5. (A) The absolute number of thymocytes is shown. (B) The percentages of thymocytes that were DN, DP, SP CD4+ and SP CD8+ thymocytes and shown. (C) The percentages of DN thymocytes that were DN1, DN2, DN3E, DN3L and DN4 thymocytes are shown. (D) The percentages of SP CD8+ and SP CD4+ thymocytes that were ISP CD8+ and TSP CD4+ thymocytes, respectively, are shown. (E) The percentages of DN3E, DN3L and DN4 thymocytes that expressed TCRβ are shown. (F) The percentages of DN1, DN2, TCRβ+ DN3E and DP thymocytes that were in the S, G2 or M phase of the cell cycle are shown. *P < 0.05, **P < 0.01.