Figure 9.

Morphine does not directly impair thymic development. FTOC was performed as described in Methods in the presence of 6 µM [M(H)] or 1 µM [M(L)] morphine, 6 µM morphine plus 6 µM naltrexone (M + N), 1 µM dexamethasone (D), or media (C). (A) The absolute numbers of thymocytes recovered after 7 days of culture are shown. (B) Thymocytes were analysed for CD4 and CD8 expression. The percentages of cells that were DN, DP, SP CD4⁺ and SP CD8⁺ thymocytes are shown. Dot plots represent one mouse from each group.