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Summary of pharmacological potency values of PF-04418948 in relevant native systems
| Functional native assay | KB value |
|---|---|
| Human myometrium | 5.4 nM (95% CI 1.0–27.9 nM, n = 4) |
| Dog bronchiole | 2.5 nM (95% CI 1.4–4.5 nM, n = 4) |
| Mouse trachea | 1.3 nM (95% CI 0.8–2.4 nM, n = 19) |
