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. Author manuscript; available in PMC: 2011 Dec 28.
Published in final edited form as: Am J Med Genet A. 2007 May 15;143A(10):1060–1070. doi: 10.1002/ajmg.a.31721

Table I. Definitions of 29 Three-Dimensional Landmarks Collected From Each HR-MRI. Landmarks Numbers (Left Side, Right Side) Are Keyed to Figure 2.

Landmark definition Surface (S) or internal (I) Bilateral (B) or midline (M) Cerebrum (C) or cerebellum (CBM)
1, 2 Most superior and lateral point of the intersection of olfactory bulb with anterior frontal lobe S B C
3, 4 Caudolateral-most point of occipital lobe S B C
5 Most posterior point on interhemispheric fissure S M C
6, 7 Centroid of posterior colliculus I B CBM
8 Midline of cerebellar declive S M CBM
9, 10 Intersection of Fissurae Intercruralis, Ansoparamediana, and Prima on cerebellar surface S B CBM
11, 12 Intersection of Fissurae Prepyramidalis and Horizontalis on dorsal surface of cerebellum S B CBM
13, 14 Most concave point of the intersection of Copula pyramidis with Uvula on surface of cerebellum S B CBM
15 Most convex point on the midline of cerebellar Uvula S M CBM
16, 17 Centroid of caudate head I B C
18, 19 Centroid of thalamus I B C
20, 21 Branching point of middle cerebral artery into cortical branches S B C
22, 23 Origin of middle cerebral artery from Circle of Willis on ventral cerebral surface S B C
24 Genu of corpus callosum at midline I M C
25, 26 Centroid of septal nucleus I B C
27 Anterior commissure at midline I M C
28 Splenium of corpus callosum at midline I M C
29 Intersection of pons with most caudal aspect of the ventral cerebral surface at midline S M C

Final three columns refer to the general location and characteristics of the landmark and the analytical subset to which the landmark belongs. Landmarks were analyzed in two subsets: the cerebrum subset (C), and the cerebellum and midbrain subset (CBM). Midbrain structures were analyzed with the cerebellum subset.