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. Author manuscript; available in PMC: 2011 Dec 28.
Published in final edited form as: Bioconjug Chem. 2009 Jul;20(7):1332–1339. doi: 10.1021/bc9000646

Figure 3.

Figure 3

The release profiles for encapsulated carboxyfluorescein (λex = 480 nm; λem = 518 nm) for the liposomes incorporating 30 mol% of the lipopeptide GPO3 in the presence and absence of MMP-9 in 25 mM HEPES buffer, pH = 8.0 containing 100 mM NaCl, 10 mM CaCl2 and 10 mM ZnCl2. For DOPC liposomes (3A), complete dye release was observed (blue circles) in the presence of 2.3 μM MMP-9 and about 25% release was observed in the absence of the enzyme (red squares). For POPC liposomes (3B), 90% of the encapsulated dye was released with 2.3 μM MMP-9 (blue circles); in the absence of the enzyme, no dye release was detected (red squares). The lines through the release profiles are the fitted curved using a biexponential rate equation.