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. Author manuscript; available in PMC: 2011 Dec 28.
Published in final edited form as: Bioconjug Chem. 2009 Jul;20(7):1332–1339. doi: 10.1021/bc9000646

Figure 6.

Figure 6

The release profiles for POPC liposome-encapsulated carboxyfluorescein (λex = 480 nm; λem = 518 nm) containing 30 mol% of lipopeptide GPO4 in the presence of cell secreted MMP-9 in 25 mM HEPES buffer, pH = 8.0 containing 100 mM NaCl, 10 mM CaCl2 and 10 mM ZnCl2 (6A). The conditioned media from MCF7 cells released 40% of the encapsulated dye (blue circles) in 30 minutes; the conditioned media from the HT-29 cells released less than 10% of the contents in 30 minutes (green squares) and the culture media did not release any contents from the liposomes (red triangles). The line through the blue circles represents the fitted curve using the biexponential rate equation. The liposomes containing 30 mol% of lipopeptide GPO3 failed to release significant amount of the encapsulated dye under identical experimental conditions with conditioned media from MCF7 (6B, blue circles) and HT-29 (6B, green squares).