Table 2.
Baseline characteristics of enrolled patients (safety population)*
| Artemether-lumefantrineN = 159 | Atovaquone-proguanilN = 53 | Artesunate-mefloquineN = 53 | |
|---|---|---|---|
| Sex - n (%) | |||
| Male | 96 (60.4) | 34 (64.2) | 31 (58.5) |
| Race - n (%) | |||
| Black | 132 (83.0) | 42 (79.2) | 44 (83.0) |
| Hispanic | 27 (17.0) | 11 (20.8) | 9 (17.0) |
| Mean Age (yr) | 25.6 | 25.1 | 25.2 |
| SD | 11.6 | 11.2 | 11.3 |
| Range | 12–56 | 12–53 | 12–56 |
| Age category - n (%) | |||
| < 18 years | 51 (32.1) | 21 (39.6) | 18 (34.0) |
| 18 to < 65 years | 108 (67.9) | 32 (60.4) | 35 (66.0) |
| Mean weight (kg) | 62.8 | 60.3 | 65.2 |
| SD | 14.4 | 14.5 | 15.4 |
| Range | 30.0–110.0 | 30.0–97.0 | 35.0–110.0 |
| Weight category - n (%) | |||
| ≥ 70 kg | 50 (31.4) | 18 (34.0) | 19 (35.8) |
| BMI ≥ 25 kg/m2 | 50 (31.4) | 11 (20.8) | 21 (39.6) |
| Mean body temperature (°C) | 37.8 | 37.7 | 37.8 |
| SD | 0.6 | 0.7 | 0.6 |
| Range | 36.5–40.0 | 36.5–40.0 | 36.0–40.0 |
| Median parasite density, asexual forms (/μL) | 3925 | 3864 | 4620 |
| Range | 1,008–44,744 | 1,030–31,124 | 1,012–35,112 |
*
BMI = body mass index; SD = standard deviation.