Table 2. Association between rs2075555 in COL1A1 and high myopia (≤-6.00 D) in a Han Chinese population.
| Phenotype | HWE | Genotype count(frequency) | Allele frequency | Allelic p | OR (95%CI) | Trend p value |
|---|---|---|---|---|---|---|
| Case (697) |
0.79 |
AA: 91 (0.13) |
A: 0.37 |
0.252 |
1.09 (0.94–1.30) |
0.239 |
|
|
|
AC: 333 (0.48) |
C: 0.63 |
|
|
|
|
|
|
CC: 273 (0.39) |
|
|
|
|
| Control (762) |
0.09 |
AA: 79 (0.10) |
A:0.35 |
|
|
|
|
|
|
AC: 374 (0.49) |
C:0.65 |
|
|
|
| CC: 309 (0.41) |