Table 3. Association between rs2269336 in COL1A1 and high myopia (≤-6.00 D) in a Han Chinese population.
| Phenotype | HWE | Genotype count(frequency) | Allele frequency | Allelic p | OR (95%CI) | Trend p value |
|---|---|---|---|---|---|---|
| Case (697) |
0.22 |
CC: 254 (0.36) |
C:0.59 |
0.699 |
1.03 (0.80–1.19) |
0.697 |
|
|
|
CG: 315 (0.45) |
G:0.41 |
|
|
|
|
|
|
GG: 128 (0.18) |
|
|
|
|
| Control (762) |
0.05 |
CC: 243 (0.32) |
C:0.58 |
|
|
|
|
|
|
CG: 403 (0.53) |
G:0.42 |
|
|
|
| GG: 116 (0.15) |