Table 5. Association between rs2269336 in COL1A1 and high myopia (≤-9.25 D) in a Han Chinese population.
| Phenotype | HWE | Genotype count(frequency) | Allele frequency | Allelic p | OR (95%CI) | Trend p value |
|---|---|---|---|---|---|---|
| Case (697) |
0.30 |
CC: 107 (0.39) |
C:0.61 |
0.266 |
1.12 (0.92–1.37) |
0.254 |
|
|
|
CG: 123 (0.45) |
G:0.39 |
|
|
|
|
|
|
GG: 46 (0.17) |
|
|
|
|
| Control (762) |
0.05 |
CC: 243 (0.32) |
C:0.58 |
|
|
|
|
|
|
CG: 403 (0.53) |
G:0.42 |
|
|
|
| GG: 116 (0.15) |