Table 2. The significant pathways (Degreeā„5) of Path-Net.
| Pathway | Significant pathway | Indegreea | Outdegreeb | Degreec |
| MAPK signaling pathway | YES | 16 | 3 | 19 |
| Citrate cycle (TCA cycle) | YES | 7 | 6 | 13 |
| Fatty acid metabolism | YES | 4 | 4 | 8 |
| Bladder cancer | YES | 1 | 6 | 7 |
| Huntington's disease | YES | 0 | 7 | 7 |
| Arginine and proline metabolism | YES | 3 | 3 | 6 |
| Renal cell carcinoma | YES | 1 | 5 | 6 |
| Alanine and aspartate metabolism | 3 | 3 | 6 | |
| Proteasome | YES | 4 | 1 | 5 |
a,b
Indegree and Outdegree represent the inward and outward relationships, respectively;
c
Degree evaluates the inferred extent of pathway interaction.