Table 1. Relative risk of TST conversion for ELISpot-positive, TST-negative contacts.
ESAT-6 | CFP-10 | Rv3873 | Rv3878 | Rv3879c | PPD | SKSDa | ||||||||
Test result | positive | negative | positive | negative | positive | negative | positive | negative | positive | negative | positive | negative | positive | negative |
TST conversion b | 3 | 38 | 4 | 37 | 7 | 34 | 3 | 38 | 8 | 33 | 26 | 15 | 21 | 20 |
TST non-conversion | 25 | 244 | 19 | 250 | 17 | 252 | 10 | 259 | 24 | 245 | 114 | 155 | 159 | 110 |
Cumulative percentage risk of conversion (95% CI) | 10.7 | 13.5 | 17.4 | 12.9 | 29.2 | 11.9 | 23.1 | 12.8 | 25 | 11.9 | 18.6 | 8.8 | 11.7 | 15.4 |
(2.2, 28.2) | (9.7, 18.0) | (5.0, 38.8) | (9.2, 17.3) | (12.6, 51.1) | (8.4, 16.2) | (5.0, 53.8) | (9.2, 17.1) | (11.5, 43.4) | (8.3, 16.3) | (12.5, 26.0) | (5.0, 14.1) | (7.4, 17.3) | (9.6, 22.8) | |
Relative risk of conversion (95% CI) | 0.80 (0.26, 2.41) | 1.35 (0.53, 3.45) | 2.45 (1.22, 4.93) | 1.80 (0.64, 5.08) | 2.11 (1.07, 4.16) | 2.10 (1.16, 3.82) | 0.76 (0.43, 1.34) | |||||||
P value | 0.68 | 0.54 | 0.02 | 0.28 | 0.04 | 0.01 | 0.34 |
Streptokinase streptodornase (SKSD), a non-tuberculosis control antigen.
TST conversion defined as an increase in induration of ≥10 mm between the 1st and 2nd TST where the first TST was <5 mm.