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. 2011 Dec 28;6(12):e29489. doi: 10.1371/journal.pone.0029489

Table 2. Sample size, the distribution of A-6G genotypes and allele frequencies, and P-values of HWE.

Sample size AA(genotype) AG(genotype) GG(genotype) A allele frequency (%) HWE(P* value)
First author Cases Controls Cases Controls Cases Controls Cases Controls Cases Controls Controls
Ge [16] 96 112 36 49 50 55 10 8 63.54 68.30 0.1558
Hu [14] 107 108 53 59 35 37 19 12 65.89 71.76 0.1078
Jiang [17] 220 235 136 169 74 62 10 4 78.64 85.11 0.5325
Kong [15] 324 187 200 104 112 77 12 6 79.01 76.20 0.0641
Liu(Han) [38] 97 90 65 59 27 27 5 4 80.93 80.56 0.6878
Liu(Tibetan) [12] 163 213 64 102 86 97 13 14 65.64 70.66 0.2927
Liu(Yi) [12] 63 82 47 52 15 27 1 3 86.51 79.88 0.8259
Qi [7] 1122 965 671 608 378 313 73 44 76.65 79.22 0.6470
Wang(Amis) [9] 107 96 89 65 17 30 1 1 91.12 83.33 0.2207
Wang(Kazakh) [18] 201 151 77 52 81 71 43 28 58.46 57.95 0.6550
Wang(Li) [11] 100 100 83 89 15 10 2 1 90.50 94.00 0.2565
Wu [10] 459 325 316 229 121 90 22 6 82.03 84.31 0.4010
Yao [19] 67 54 33 30 31 21 3 3 73.49 75.00 0.7855
Ying [20] 243 258 138 161 86 83 19 14 74.49 78.49 0.4473
Yue [21] 73 82 3 1 19 27 51 54 80.77 82.32 0.2354

Abbreviations: HWE, Hardy–Weinberg equilibrium.

*The P-value of HWE determined by the χ2 test.