Figure 3. Fraction of endogenous host immune cell subsets following TBI regimens.

Thy1.2⁺ host mice received a preparative regimen with either single-dose irradiation at the day of T cell transfer or a fractionated (F) dose of irradiation over six times twice daily up to the amount indicated in the legend followed by the adoptive transfer of 1 x 10⁶ Thy1.1⁺ effector pmel-1 CD8⁺ T cells (P) with rhIL-2 (I). Absolute numbers of Thy1.1⁺ pmel-1 vs.: (A) endogenous Thy1.2⁺ CD8⁺ T cells; (B) endogenous CD4⁺ T cells; (C) NK 1.1⁺ cells; and (D) Gr1⁺ cells were determined six days after the pmel-1 T cell transfer in the spleen. Error bars represent SEM. Experimental data are derived from three mice collected and individually evaluated. Experiment was repeated independently with similar results.