Table 1.
Serum alanine aminotransferase, tumor necrosis factor-α, IL-1β and IL-6 levels in rats after administration of lipopolysaccharide (n = 6, mean ± SE)
| Sham | BDL | Sham + LPS | BDL + LPS | |
| ALT (U/L) | 41.2 ± 3.2 | 119.7±11.1a | 73.2 ± 7.7 | 305.0 ± 37.5a |
| TNF-α (pg/mL) | 27.9 ± 3.2 | 66.0 ± 6.5a | 861.1 ± 44.2 | 2364.7 ± 196.3a |
| IL-1β (pg/mL) | 19.7 ± 2.6 | 56.0 ± 7.6a | 1073 ± 97.7 | 2373.0 ± 265.1a |
| IL-6 (pg/mL) | 30.7 ± 3.5 | 60.2 ± 5.8a | 4476.7 ± 430.2 | 10802.0 ± 853.2a |
a
P < 0.01 for bile duct ligation group vs Sham group. BDL: Bile duct ligation; LPS: Lipopolysaccharide; ALT: Alanine aminotransferase; TNF-α: Tumor necrosis factor-α.