Table 1.

In vitro and in vivo substrates of PAS kinase.

Putative substrate	Site(s)	Species	Evidence	Reference
Glucose-partitioning
Pancreatic duodenal homeobox 1 (PDX1)	Thr152	H. sapiens	in vitro phosphorylation	[40]
Glycogen synthase (Gsy)	Ser640	H. sapiens	in vitro phosphorylation; copurification	[16]
	Ser654	S. cerevisiae	In vitro phosphorylation;	[9]
UDP-glucose pyrophosphorylase (Ugp1)	Ser11	S. cerevisiae	in vitro & in vivo phosphorylation	[7,9,10]
Translation-related
Translation initiation factor eIF1A	Ser125	S. cerevisiae	in vitro phosphorylation	[9]
	Thr432	H. sapiens	in vitro phosphorylation; coimmunoprecipitation; colocalization; yeast 2-hybrid	[35]
Caf20	Ser58 Ser59 c-term*	S. cerevisiae	in vitro phosphorylation	[9]
Sro9	Thr101 Thr103	S. cerevisiae	in vitro phosphorylation	[9]
Alanyl tRNA Synthetase (Alars)	Ser732	H. sapiens	in vitro phosphorylation	[48]
Basic Transcription Factor 3(BTF3)	Thr38	H. sapiens	in vitro phosphorylation	[48]
Ribosomal Protein S3A (RPS3A)	Ser154	H. sapiens	in vitro phosphorylation	[48]
Ribosomal Protein S2		H. sapiens	in vitro phosphorylation	[48]
Ribosomal Protein S6		H. sapiens	in vitro phosphorylation	[48]
Ribosomal Protein S8		H. sapiens	in vitro phosphorylation	[48]
Ribosomal Protein S10		H. sapiens	in vitro phosphorylation	[48]
Ribosomal Protein S14		H. sapiens	in vitro phosphorylation	[48]

^*multiple phosphorylation events on the C-terminal 68 amino acids were reported.