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. 2011 Sep 26;125(1):196–208. doi: 10.1093/toxsci/kfr253

FIG. 3.

FIG. 3.

CPF treatment has no major effect on spine number on apical CA1 dendrites in the first week following treatment. (A) Total synaptic spine density is unaffected by CPF exposure at 1 week following treatment. Magnification of dendritic spines (×100) in Golgi-stained CA1 pyramidal neurons from vehicle-treated (B) and CPF-treated mice (C). Scale bars: 10 μm. Changes in spine density between vehicle-treated and CPF-treated mice are not dependent on dendritic branch order for apical (D) or basilar segments (F). Legend in panel D also applies to panels E, F, and G. Spine density is slightly decreased in CPF-treated mice at apical segments 270–310 μm from the soma (E) but not at basilar segments (G). *p < 0.05 compared with vehicle. For all panels, data represent means ± SEM.