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Targeting and encapsulation of proteins into BMCs nano-cages. In some cases (panel A), a stretch of ~15-20 aminoacids (in green) located at the N-terminus of the inner cargo protein (in red) directs and binds it to specific sites on the inner surface of the shell protein (in blue). For other bacterial microcompartments (panel B), the cargo protein (in red) is synthesized together with the shell-forming domain (in blue) from one unique gene.
