FIGURE 4.

C8 C-1-P inhibits IκB degradation and phosphorylation of the NF-κB p65 subunit. Cells were treated with 10 μm ghost or C8 C-1-P liposomes with or without 100 ng/ml LPS for 45 min. IκB and ERK protein levels (A) or p-p65 levels (B) were measured by Western blotting. Densitometry results are displayed on the graph on the right. Blots are representative of at least three independently performed experiments. Densitometry was measured using ImageJ software. Error bars, S.E. *, p < 0.05; **, p < 0.01; ***, p < 0.001.