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. 2011 Oct 25;286(52):44691–44701. doi: 10.1074/jbc.M111.303917

FIGURE 4.

FIGURE 4.

Contribution of the intracellular regions to regulation of P2X receptor time-course. a, shown is a schematic representation of P2X receptors and chimeras. inter, intermediate. b, representative currents were mediated by application of 100 μm ATP to chimeric receptors expressed in Xenopus oocytes. c, a histogram summary shows the time to 50% current decay during the continued presence of ATP. d, shown is a schematic representation of P2X receptors and chimeras. e, representative currents were mediated by application of 100 μm ATP to chimeric receptors expressed in Xenopus oocytes. c, a histogram summary shows the percentage of current remaining at the end of a 20-s 100 μm ATP application. **, p < 0.01; ***, p < 0.001 (n = 5–17).