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. 2011 Dec;92(6):400–412. doi: 10.1111/j.1365-2613.2011.00789.x

Figure 4.

Figure 4

Effects of tetrodotoxin (TTX) (1 μM), l-NNA (1 mM) and MRS 2179 (20 μM) on the spontaneous mechanical activity of the circular muscle layer of the mid-colon. (a, c, e) Representative tracings showing the contractile activity of the strips from control (left panel) and diabetic mice (right panel) after TTX (a), l-NNA (c) or MRS 2179 (e) exposure. (b, d) Bar diagrams showing the changes in amplitude and frequency of circular muscle layer contractions in samples from both groups after TTX (b) or l-NNA (d) addition; paired Student's t-test, *P<0.05, **P<0.01 and ***P<0.001.