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Human leucocyte antigen (HLA)-B*0702 binding capacity of herpes simplex virus (HSV)-2 VP22 (UL49) epitope variants identified in 120 sampled genes
| Epitope | Sequences | Variant frequency | IC50 (nm) | Probable HLA-B*0702 binder? |
|---|---|---|---|---|
| HSV2:UL4949-57 | RPRGEVRFL | 93/120 (78%) | 0·23 | Yes |
| RPMREVRFL | 26/120 (22%) | 2·1 | Yes | |
| HSV2:UL4982-90 | RPRRSASVA | 110/120 (92%) | 0·64 | Yes |
| RPRHSASVA | 10/120 (8%) | 0·59 | Yes | |
| HSV2:UL49131-140 | APATPATDPA | 59/120 (49%) | 196 | Yes |
| ASATPATDPA | 61/120 (51%) | > 70 000 | No |
