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. Author manuscript; available in PMC: 2012 Aug 10.
Published in final edited form as: Cell Immunol. 2011 Aug 10;271(2):342–349. doi: 10.1016/j.cellimm.2011.07.014

Figure 2.

Figure 2

Time course of induction of IRF5 and IRF7 protein expression in poly (I-C) stimulated THP-1 cells. Cells were incubated with poly (I-C) for up to 18 h at 10 μg/mL and analyzed by Western blot analysis. Poly (I-C) stimulated fibroblast-like synviocyte (FLS) lysate was used as a positive control. Poly (I-C) was most effective at inducing IRF7 and IRF5 at 10 μg/mL for 18 h (22.65-fold ± 3.65; n = 3 and 29.65-fold ± 4.37; n = 3 respectively). Top panel shows a representative Western blot, and the bottom panel shows combined densitometry results for three independent experiments.