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. 2011 Dec 1;26(1):27–36. doi: 10.1210/me.2011-0042

Fig. 3.

Fig. 3.

FXR displays antiinflammatory activities in the lung after LPS treatment. Quantitative real-time PCR analysis of the expression of proinflammatory genes in lungs from WT and FXR−/− mice that were treated with a single dose of LPS (4 μg/10 g of BW) or PBS [as controls (Con) (Veh)]. RNA expression levels of TNFα (A), IFNγ (B), IL-6 (C), iNOS (D), and MCP1 (E) were analyzed on d 1 (D1) after LPS or PBS treatments. F, RNA levels of P-selectin expression were analyzed on d 1 (D1) and d 2 (D2) after LPS treatment. *, P < 0.05; **, P < 0.01. Con, Control; Veh, vehicle.