Figure 5. Drug combination and drug-therapy network.

A drug is linked to its therapy, additionally drugs are linked if they can be combined, where the third level of the ATC code was considered because other levels are either too general to reveal pharmacological differences or too specific with too few common annotations left. Drugs are depicted by diamonds, therapies (according to ATC) as circles, and the color of each drug node denotes its therapeutic category (the first level of ATC code). Cases detailed in the text are highlighted within dashed lines.