Table 1. Properties of preoptic GABAergic w-t and Kv4.2−/− neurons.
Parameter | w-t | n | Kv4.2−/− | n |
r.m.p. (mV) | −52.3±4.4 | 14 | −50.6±5.1* | 15 |
Rinput (MΩ) | 407±62 | 14 | 427±53 | 15 |
S. f. r. (Hz) | 10.2±3.7 | 14 | 9.4±3.5 | 15 |
AP amplitude (mV) | 77.2±4.4 | 14 | 78.3±5.7 | 15 |
AP threshold (mV) | −43±3 | 14 | −44±4 | 15 |
AP halfwidth (mV) | 0.8±0.1 | 14 | 0.9±0.1 | 15 |
AHP amplitude (mV) | −17.8±3.1 | 14 | −19.2±3.2 | 15 |
AHP time to peak (ms) | 5.5±3.4 | 14 | 4.9±3.9 | 15 |
AHP decay (mV/ms) | 0.23±0.22 | 14 | 0.25±0.2 | 15 |
Peak IA density at 0 mV (pA/pF) | 58.6±19.5 | 14 | 41.8±12.9* | 15 |
ISS density at 0 mV (pA/pF) | 45.4±19.5 | 14 | 82.3±27.5** | 15 |
Values are presented as mean ± S.D., * and ** indicate P<0.05 and P<0.01, respectively (unpaired t-tests), (n)-number of cells.