Skip to main content
. Author manuscript; available in PMC: 2011 Dec 29.
Published in final edited form as: Immunol Rev. 2009 Mar;228(1):23–40. doi: 10.1111/j.1600-065X.2008.00758.x

Figure 2. Lyn-deficient mice develop splenomegaly due to myeloproliferation and extra-medullary erythropoiesis.

Figure 2

(A) Spleen weight of WT and lyn−/− mice monitored over 60 weeks. (B) Splenic cells derived from WT and lyn−/− mice stained with Wright/Giemsa. (C, D) Flow cytometric analysis of WT and lyn−/− splenocytes from 6 and 28 week old mice. Percentages of Mac-1/Gr-1 double positive myeloid cells (C) or Ter-119 positive erythroid cells (D) are reported.