Fig. 6.

Macroscopic photographs and histology of the denervated and non-denervated C57BL/6 ear wound 50 days post-wounding. (a) Macroscopic photograph of the non-denervated C57BL/6 wound 50 days post-wounding showing limited wound closure (figures and arrows correspond to cross-sections sampled for histology displayed below). Masson's Trichrome stained tissue sections; (a1) through distal wound margin and (a2) through proximal wound margin showing a bulbous aggregate of cartilage. (b) Photograph of the C57BL/6 denervated ear wound 50 days post-wounding showing extension of wound area towards the ear tip (b1) through the distal tip of the ear wound displaying extensive necrosis and failure to re-epithelialise, and (b2) through the proximal ear wound margin showing re-epithelialisation, but no evidence of cartilage formation or dermal extension. Scale bars: 100 μm.