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Correlation between mRNA expression of four transcription factors PXR (a), RXRα (b), CAR (c), and HNF4α (d) and CYP3A4 in 93 human livers (cohort 2). CYP3A4 mRNA levels were positively correlated with mRNA levels of each of the four transcription factors, with correlation coefficients R ranging from 0.37 to 0.53 (P≤0.001). Data are in Log10 scale.
