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. Author manuscript; available in PMC: 2011 Dec 30.
Published in final edited form as: Circ Res. 2011 Aug 19;109(5):578–592. doi: 10.1161/CIRCRESAHA.111.247965

Figure 2. Typical manifestations of generalized arterial calcification of infancy (GACI) caused by mutations in ENPP1.

Figure 2

A, Cardiac ultrasound (suprasternal long-axis view) of a 4-week-old boy; note increased echogenicity of the wall of the ascending aorta (arrow-heads). B, Radiograph of the left hand of a 2-week-old boy showing periarticular calcifications (arrow). C, Cross section of the left coronary artery from a boy who died of myocardial infarction at the age of 9 weeks, showing calcification at the level of the internal elastic lamina (arrows) and intimal proliferation (hematoxylin and eosin staining). Ao indicates aorta, LA; left atrium.