Table 1.

Demographic and Clinical Characteristics of Outpatients with Pulmonary Embolism Stratified According to 90 day Outcome Status^*

Variable	(−) Mortality (n = 271)	(+) Mortality (n = 34)	P-value	(−) Composite Endpoint (n = 244)	(+) Composite Endpoint (n = 61)	P-value
Age (mean, yrs)	60.6	69.1	0.005	60.5	65.5	0.04
Demographic Factors (%)
≥ 65 years	45.4	70.6	0.005	44.7	62.3	0.014
Male	40.2	58.8	0.039	39.7	52.5	0.072
Clinical History (%)
Active malignancy†	27.7	61.8	<0.001	27.5	47.5	0.003
History of prior VTE	14.4	11.8	0.67	15.6	8.2	0.12
History of prior cerebrovascular accident	7.0	14.7	0.15	7.4	9.8	0.53
History of chronic lung disease	18.8	26.5	0.31	16.4	32.8	0.006
History of congestive heart failure	10.7	26.5	0.018	9.8	23.0	0.009
Recent ICU discharge†	9.2	23.5	0.023	7.79	23.0	0.002
Recent severe infection†	18.5	41.2	0.004	17.2	36.1	0.002
Recent trauma†	14.8	11.8	0.63	12.7	21.3	0.10
Recent hospitalization†	37.1	63.6	0.004	36.1	55.9	0.006
Recent surgery†	26.0	32.4	0.60	25.6	31.2	0.45
Recent fracture†	6.3	5.9	0.93	6.6	4.9	0.63
Presentation characteristics
Heart rate > 100 bpm‡ (n = 294)	22.5	28.2	0.43	23.0	23.2	0.98
Systolic BP < 100 mm Hg‡ (n = 295)	7.5	20.5	0.016	6.6	18.8	0.003
Pa02 < 60 mm Hg‡ (n = 92)	31.8	28.8	0.78	29.9	27.8	0.81
New diagnosis of concomitant DVT	43.5	50.0	0.48	44.3	44.3	1.00

^*Table presents results of initial screening to identify candidate variables potentially associated with our primary composite endpoint at 90 days after the index PE event. Variables with p-value < 0.25 were included in the multivariable regression models.

^†Recent = active or occurring within 3 months of diagnosis of VTE

^‡Missing heart rate data, systolic BP data on 11, 10, patients respectively. Arterial blood gas was not performed or performed on oxygen in 213 patients. Missing values were imputed as normal in analyses.

PE = pulmonary embolism; DVT = deep vein thrombosis; VTE = venous thromboembolism; IVC = inferior vena cava