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. Author manuscript; available in PMC: 2011 Dec 30.
Published in final edited form as: J Org Chem. 2007 Mar 27;72(9):3207–3210. doi: 10.1021/jo0624694

TABLE 4.

Preparation and Cyclization of α-Aryl-α-diazo Ketones

entry α-diazo ketone yield (%)a product yield (%)
1 graphic file with name nihms-62089-t0023.jpg 99 graphic file with name nihms-62089-t0024.jpg 61b
2 graphic file with name nihms-62089-t0025.jpg 89 graphic file with name nihms-62089-t0026.jpg 40d
3 graphic file with name nihms-62089-t0027.jpg 95 graphic file with name nihms-62089-t0028.jpg 79
4 graphic file with name nihms-62089-t0029.jpg 95 graphic file with name nihms-62089-t0030.jpg 71b
5 graphic file with name nihms-62089-t0031.jpg 80 graphic file with name nihms-62089-t0032.jpg 42b
6 graphic file with name nihms-62089-t0033.jpg 95 graphic file with name nihms-62089-t0034.jpg 81b
a

Yield of the diazo ketone.

b

Yield after equilibration of the epimeric products with DBU.

c

Previously reported ( Ref. 12).

d

The product is a mixture of ring fusion diastereomers.