Figure 2.

Overall time chart of the study and per patient (M = month). Figure 2 shows the overall time-chart of the study and per patient. Each hospital has a period of twelve months to include 35 patients in the study. The total intervention period of hospitals is fifteen months (per patient twelve weeks). The first follow-up period is six months after the intervention period (M15) and the second, twelve months after the intervention period (M27). Each patient will be included in the study for 15 months.