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. 2011 Nov 23;1:48. doi: 10.1186/2110-5820-1-48

Table 3.

Resume of recommendations for monotherapy or combination therapy in CAP

Ambulatory setting Previously healthy patients Monotherapy

Previous antibiotic therapy Combination or respiratory fluoroquinolone

Comorbidities without previous antibiotic therapy Monotherapy with macrolides or respiratory fluoroquinolone

Comorbidities and previous antibiotic therapy Combination therapy
Nursing home without hospitalization CAP Combination therapy

Hospitalized CAP Moderate disease Monotherapy with respiratory fluoroquinolones or combination therapy

Severe CAP Combination therapy

Bacteremic pneumococcal CAP Combination therapy

CAP and shock Combination therapy

Ventilation support Combination therapy