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. 2012 Jan 1;23(1):1–6. doi: 10.1091/mbc.E10-04-0335

FIGURE 2:

FIGURE 2:

Potential actions of paclitaxel on tumor cells. Green arrows show cell cycle transitions. Red arrows show the only well-characterized drug action—killing cancer cells that enter mitosis. Blue arrows show hypothetical mechanisms for killing quiescent cancer cells that would provide solutions to the proliferation rate paradox.