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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Int J Neuropsychopharmacol. 2011 Jul 22;15(8):1073–1086. doi: 10.1017/S1461145711001180

Fig 1.

Fig 1

Experimental designs used for testing the behavioral and biochemical responses to cysteamine treatment in mice. (1a) Cysteamine (150 mg/kg) or water (vehicle) was administered through drinking water to heterozygous reeler mice (HRM) and wild-type (WT) mice for 14 days. On day 14, mice were killed and brains removed for biochemical analyses. (1b) Cysteamine (150 mg/kg) or water (vehicle) was administered through drinking water to HRM and WT mice for 30 days. In order to study the behavioral responses to cysteamine or vehicle treatment, animals were tested for behavioral studies from day 25 to day 29. On day 30, mice were killed and brains removed for biochemical analyses. (2) Cysteamine (150 mg/kg) or water (vehicle) was administered through drinking water to TrkB knockout and WT mice for 30 days. On day 30, mice were killed and brains removed for biochemical analyses.