FIGURE 4.

Reactions catalyzed by enolase superfamily members. The various boxes enclose reactions catalyzed by the seven subgroups that have been recognized. 2-PGA, 2-phosphoglycerate; PEP, phosphoenolpyruvate; MAL, β-methylaspartate ammonia lyase; SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid; OSB, o-succinylbenzoic acid; AE Epim, l-Ala-d/l-Glu epimerase; GalD, d-galactonate dehydratase; GlcD, d-gluconate dehydratase; FucD, l-fuconate dehydratase; TarD, d-tartrate dehydratase; RhamD, l-rhamnonate dehydratase; AraD, d-arabinonate dehydratase; GalrD/TalrD, galactarate dehydratase/l-talarate dehydratase; XylD, d-xylonate dehydratase; GlucD, d-glucarate dehydratase; ManD, d-mannonate dehydratase.