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Summary of kinetic properties of IDE, IDER429S, and IDEK898A,K899A,S901A with Abz-GGFLRKHGQ-EDDnp as a substrate
| IDE | IDER429S | IDEK898A,K899A,S901A | |
|---|---|---|---|
| Vmax (nmol/min/mg) | 47.2 ± 1.7 | 42.3 ± 3.2 | 140.8 ± 5.5 |
| kcat (min−1) | 5.2 ± 0.2 | 4.7 ± 0.3 | 15.5 ± 0.6 |
| Km (mm) | 9.6 ± 0.7 | 21.3 ± 2.4 | 17.3 ± 1.0 |
| Hill coefficient | 2.1 ± 0.3 | 1.7 ± 0.2 | 1. 7 ± 0.1 |
