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. 2011 Oct 28;123(1):105–117. doi: 10.1007/s00401-011-0893-0

Fig. 2.

Fig. 2

Relative abundance of PHF-tau methylation and ubiquitylation. Relative abundance was calculated based on the spectral counts of the modified peptide/(modified peptide + unmodified peptide). Only sites having total spectral counts >3 are shown. Inset quantifies K254 methylation (41%) and ubiquitylation (1%). K254 was the most abundant methylated site identified on PHF-tau (spectral count = 17) and the only site on PHF-tau identified in methylated and ubiquitylated forms