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Time courses of the plasma concentrations of aripiprazole (APZ) and dehydroaripiprazole (DAPZ) in CYP2D6 EMs and IMs with and without of fluvoxamine (FLV) following a single oral dose of 3 mg APZ (mean + standard deviation, semilogarithmic scale). Figure at the top right shows the 0–24 h plasma concentrations of APZ (mean + standard deviation, actual scale). EM Extensive metabolizer, IM intermediate metabolizer
