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Clinical efficacy rates stratified by fAUC0−24/MIC obtained at the phase III study
| fAUC0−24/MIC (h) | Efficacy rate (cure/number of patients) | 95% confidence interval for efficacy rate |
|---|---|---|
| >30 | 91.8% (56/61) | 81.9 –97.3% |
| ≤30 | 40.0% (2/5) | 5.3– 85.3% |
| >28 a | 91.8% (56/61) | 81.9 –97.3% |
| ≤28 | 40.0% (2/5) | 5.3– 85.3% |
fAUC0−24/MIC, Unbound AUC/minimum inhibitory dose ratio
aClassification and regression tree (CART)-derived split
