Table 6.
Results of logistic regression analysis of fAUC0-24/MIC affecting the probability of clinical cure by garenoxacin (n = 66, phase III data)
| Variable | Coefficient (β) | Standard error | Wald χ2 | p value | Odds ratio |
|---|---|---|---|---|---|
| Logistic regression analysis by continuous valuea | |||||
| Intercept | −0.4565 | 1.0317 | − | − | − |
| fAUC0−24/MIC | 1.0865 | 0.4526 | 5.76 | 0.0164 | 2.964 |
| Logistic regression analysis by categorical valueb | |||||
| Intercept | −0.4055 | 0.9129 | − | − | − |
| fAUC0−24/MIC > 28 h | 2.8214 | 1.0253 | 7.57 | 0.0059 | 16.80 |
fAUC0−24/MIC > 28 h and fAUC0−24/MIC ≤ 28 h were coded as 1 and 0, respectively
aThis value was transformed (common logarithmic transformation)
bVariable was categorized by CART-derived breakpoint