Fig. 4.

The effect of the KLN-205 cell culture confluence on FBPase localization and mitotic index. a The intensity of FBPase-related immunofluorescent signal and subcellular localization of the enzyme changes during the growth of the cell culture. Scale bar 30 μm. The changes of culture density (b) and mitotic index (c) during the KLN-205 cell culturing. d Variation of FBPase nuclear localization expressed as a nuclear/cytoplasmic immunofluorescence ratio. Each value represents the mean and standard deviation of at least three independent experiments. A p value less than 0.05 was considered as significant