Fig. 8.

The effect of serum starvation on FBPase localization and on proliferative activity of the KLN-205 cells. The influence of serum withdrawal on: a immunostaining for proliferation marker (Ki-67) and the mitotic index; b the amount of FBPase in the KLN-205 cells. To exclude the effect of the culture confluence, both experiments were performed at comparable cell culture density. c The results of serum re-addition on Ki-67 immunolabeling. d Accumulation of FBPase and CycA in cell nuclei during serum-stimulated cell cycle entrance. All quantitative data are presented as a mean ± SD