Table 4. Estimation of allelic selection coefficients per generation in the different competition assays (the subscript refers to the mutant T63, T103, or T121).

Parameter	Estimate$(\times {10}^{-3})$	SEeq $(\times {10}^{-3})$	Sign.
α	−4.13	0.14	***
β63	−12.27	0.22	***
γ63	5.28	0.22	***
τ63	−0.13	0.30	NS
β103	−17.89	0.22	***
γ103	−2.23	0.22	***
τ103	−1.71	0.30	**
β121	−2.81	0.22	***
γ121	0.55	0.22	*
τ121	−0.48	0.30	NS

α is the cost of the marker (bacteria expressing the fluorescent proteins CFP having a 0.4% cost relative to those expressing YFP). β are the allelic effects of the three random mutations. γ are the epistasis between the random mutations and the marker. τ measures departure from transitive genotypic fitness. SE_eq gives a measure analogous to standard error and is a quarter of the support range. Sign. (significance) indicates whether the estimates are different from zero (LRT). NS, nonsignificant. All figures are multiplied by 1000. *** P-value <0.001; ** P -value <0.01.