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. Author manuscript; available in PMC: 2012 Jan 2.
Published in final edited form as: Neurosci Lett. 2010 Mar 1;474(1):17–21. doi: 10.1016/j.neulet.2010.02.064

Figure 2. Exogenous estrogen receptor mediated L-PGDS promoter activity in U251 glial cell line.

Figure 2

In cells over-expressing ERα-only, 10-11M and 10-10M of estradiol produced 3-fold and 2-fold stimulation over control (two-way ANOVA; **p<0.0001, and *p<0.05, respectively). In the non-transfected cells (NT), produced 1.7 fold stimulation over control (*p<0.05). Co-expression of ERα and ERβ led to a significant attenuation of the activity at the highest concentration of estradiol (one-way ANOVA; †p<0.05). Basal expression of the pGL3-Enhancer vector was unchanged in all groups (data not shown). Data are the mean± SEM (n=8 for all groups).

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