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Sequence changes of the Q461e2 mutants. The amino acid sequence of the parental, wild type Q461e2 in the relevant regions of the transmembrane domain, gp41, are shown. Differences in the mutant envelope variants are indicated. The clone names are shown to the left. HR1 and HR2 refer to heptad repeats 1 and 2, respectively and MPER refers to the membrane proximal external region of gp41.
