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Lack of effect of DHEA or testosterone on IL-1β–induced collagen degradation by corneal fibroblasts. Cells were cultured in collagen gels with (white bars) or without (gray bars) IL-1β (0.1 ng/ml) and in the presence of the indicated concentrations of DHEA or testosterone for 36 h, after which the amount of degraded collagen was determined. Data are means±SEM of quadruplicates from an experiment that was repeated three times with similar results.
