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. 2011 Dec 8;3(11):1098–1109. doi: 10.18632/aging.100396

Table 1. Results of Drosophila life span experiment.

Mean lifespan Log-rank test
Trial Food Strain Treatment N days χ2 P % change
1 7.5 mM (Paraquat) Oregon-R (Male) Control 99 7
RES-50 95 8 10.47 0.0012 +14.3*
THC-50 97 9 12.24 0.0001 +28.5*
THC-100 106 9 9.556 0.0020 +28.5*
THC-150 91 8 7.448 0.0063 +14.3*
C-50 106 6 2.728 0.0986 − 14.3ns
C-100 99 6 1.179 0.2775 − 14.3ns
C-150 103 6 3.141 0.0764 − 14.3ns
2 7.5 mM (Paraquat) yellow white foxo−/− (Male) Control 71 5
RES-50 62 5 0.570 0.4499 0.0ns
THC-50 57 6 0.660 0.4147 +20.0ns
3 STD yellow white (Female) Control 79 47
THC-20 80 54 10.510 0.0012 +14.8*
THC-50 78 57 11.509 0.0034 +21.2*
RES-50 72 49 11.95 0.0026 +5.2*
yellow white (Male) Control 75 38
THC-50 80 45 11.05 0.0009 +18.4*
Organ-R (Male) Control 70 46
C-20 73 44 0.2584 0.6114 − 4.3ns
C-150 74 44 0.2845 0.5938 − 4.3ns
4 STD foxo−/− (yw) (Male) Control 76 33
RES-50 76 25 1.559 0.2899 − 24.2ns
THC-50 77 30 1.123 0.2118 − 9.1ns
d4EBP−/− (yw) (Male) Control 79 31
RES-50 70 28 7.466 0.0063 − 9.6*
THC-50 77 33 0.029 0.8136 +6.5ns
5 STD Sir2−/df (yw) (Male) Control 78 32
RES-50 80 27 0.2766 0.0787 − 15.6ns
THC-50 78 27 3.0910 0.5990 − 15.6ns
*

indicates significant difference from control (P < 0.01)

ns

represented no significant difference (P > 0.05)

STD: Standard, RES: resveratrol, THC: tetrahydrocurcumin, C: curcumin