Table 1. SkQ1 retards age-dependent increase in heart mass of female BALB/c mice.
Group | Age, months | nmol SkQ1/kg per day | Number of animals | Heart mass, mg (M±m) |
---|---|---|---|---|
1 | 3 | - | 15 | 115 ± 3 |
2 | 24 | - | 14 | 157 ± 9 |
3 | 24 | 1 | 15 | 139 ± 4 |
4 | 24 | 30 | 15 | 139 ± 4 |
5 | 24* | 0.05/140 | 14 | 146 ± 6 |
Mice received 0.05 nmol SkQ1/kg per day during first 595 days of life and 140 nmol SkQ1/kg per day during the next 130 days.